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TOP STORIES
SaturdayNovember212009



x59
News drug helps erase memory and limit PTSD
11/12/2009 8:58 AM
By: Ivanhoe Broadcast Services

In one preliminary trial, investigators found the pill "significantly reduced physiological responses" in the patients.  
According to the National Institute of Mental Health, posttraumatic stress disorder, or PTSD, is an anxiety disorder that some people get after seeing or living through a dangerous event.

The intense fear triggers split-second changes in the body to defend against danger. In PTSD, this reaction is changed or damaged. People with PTSD may feel stressed or frightened even when they are no longer in danger.

Anyone can develop PTSD at any age. War veterans and survivors of physical and sexual abuse are commonly diagnosed with the disorder. Not everyone with PTSD has been through a dangerous event. Some people develop PTSD after a friend or family member experiences danger or is harmed.
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For more information:
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Ronald Najman
Communications and Special Projects
SUNY Downstate Medical Center
Brooklyn, NY
(718) 270-2696
ron.najman@downstate.edu

The sudden, unexpected death of a loved one can also cause PTSD.

It sounds like science fiction, but some researchers are studying whether certain drugs can erase or dim bad memories. The possibility of memory blocking has some ethicists concerned.

Felicia Cohn, Ph.D., is the director of medical ethics at the University of California, Irvine. She said erasing memories may be erasing someone's identity.

 WATCH THE VIDEO
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Erasing Memories

News 8’s Todd Boatwright explores the science and ethics behind some controversial therapies.



"If you start changing somebody's memories, you can raise the question of whether or not you're changing their identity in some fundamental way," Cohn said.

According to her, even bad memories teach us important lessons.

"Whether it means we become more protective with our children or we lock our doors more often at night, or you know, even subtle behavior changes can really make a big difference in the way we live," Cohn said.

Researchers in Brooklyn are studying the drug known as "ZIP" in animals. They conducted an experiment where they put the animals on a turntable. One region of the table delivered a mild foot shock, so the animals learned to stay away from that area. After the researchers injected ZIP into their brains, the rats went straight to the spot that shocked them, meaning they forgot what they had learned.

Anyone can develop PTSD at any age.  
Researchers from Harvard and elsewhere have been studying whether the drug propranolol can dim the emotional response to memories in people with PTSD.

In one preliminary trial, investigators found the pill "significantly reduced physiological responses" in the patients. Researchers said the drug works by influencing the reconsolidation of memories, which is the shaping of already-formed -- or consolidated -- memories.

In another recent study involving the drug, researchers trained 60 people to associate a picture of a spider with an electric shock.

After the conditioning, students who were given propranolol before seeing the picture were not startled, while the other students were.

Researchers are also studying the effects of other drugs for memory editing. Some of these therapies include painkillers, anti-nausea drugs and RU486, which is best known as the "abortion drug."



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Troubled Waters
News 8's Jenna Hiller explored the troubled waters in Central Texas and traveled down the Colorado River in search of information. Click on the links to watch, read and interact.

Part 1: Regional cooperation drying out
Part 2: Texas rice farmer takes on water wars
Part 3: Security of supply saturates perception
Part 4: Bad news travels near and far
Part 5: Bad news travels near and far

Where does your water come from?

Join us on Dec. 1st for the Sons of Anarchy Season Finale Party at Texas Custom Choppers.

For News 8's continuing coverage of the Fort Hood mass shootings visit our Fort Hood Shooting section, watch video from reporters in the field and press conferences with officials, and view our photo galleries: The Day Of The Shootings | The Memorial | The Victims
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